A high burden of metabolic risk factors may increase the risk of hepatocellular carcinoma (HCC) in men with chronic hepatitis B virus (HBV) infection, a study has shown. Importantly, smoking exerts a significant effect on the said association.
Inappropriate prescription of anaerobic antibiotics to intensive care unit (ICU) patients admitted with pneumonia frequently occurs, with the prescription associated with prolonged length of stay (LOS) in the ICU, a study has found.
Testing both expectorated saliva and nasopharyngeal aspirates (NPAs) can substantially improve the detection of respiratory viruses as compared with testing of NPA alone, although the viral load is lower in the saliva than in the NPA for most patients, according to a study.
The TV003 tetravalent dengue vaccine is well-tolerated and produces a strong antibody and immune response in patients who have previously been exposed to other Flaviviruses, a new randomized controlled trial has shown.
Treatment with tenofovir disoproxil fumarate for hepatitis B virus infection appears to be safe and effective in pregnancies exhibiting a high viral load, potentially preventing vertical transmission of the disease, according to a meta-analysis.
Use of statins may significantly reduce the risk of hospitalization for bacterial infections, with the protective effect similar in populations with or without diabetes, irrespective of cardiovascular events or other comorbidities, a study suggests.
The risk for viral reactivation with biologic therapies is negligible in low-risk patients without hepatitis seropositive for hepatitis B or C virus (HBV and HCV, respectively) core antibody, a recent study has found. However, biologic therapies pose a significant risk in patients with chronic HBV infection, stressing the need for antiviral prophylaxis.