Top Medical News
Yesterday
Response to herpes zoster vaccine in elderly nursing home residents is significantly associated with serum C-reactive protein (CRP) concentration and presence of congestive heart failure, a study has found.
5 days ago
While propensity score (PS) matching yielded no significant difference in the sustained virological response 24 weeks after therapy (SVR24) rates between telaprevir (TPV) with pegylated-interferon and ribavirin (PR) and boceprevir (BOC)/PR, PS matching is still a useful tool for eliminating the bias in nonrandomized studies and assessing treatment efficacy in real world settings, a new study shows.
8 days ago
Administering trivalent inactivated influenza vaccine (IIV) during pregnancy appears to reduce all-cause acute lower respiratory tract infection (ALRI) hospitalization among neonates during the first 3 months of life, suggesting that the vaccine has a potentially protective effect on subsequent bacterial infections that influenza may predispose infants to.
11 days ago
The vonoprazan-based triple therapy is superior to proton pump inhibitor-based triple therapy in terms of Helicobacter pylori eradication, although the two regimens show comparable tolerability and incidence of adverse events, according to a review and meta-analysis.
13 days ago
There appears to be a substantial number of patients with uninfected diabetic foot ulcer (DFU) who will develop an infection prior to healing, with risk factors including initial presentation of a deep ulcer, previous ulcer, peripheral neuropathy, foot deformity, younger age and female sex, according to a study.
15 days ago
Patients with inflammatory bowel disease (IBD) who are treated with corticosteroids, immunosuppressants and biologics have a low risk of pneumonia caused by Pneumocystis jirovecii (PJP), a population-based cohort study has shown. This suggests that routine administration of PJP prophylaxis in this population may not be warranted.
Jairia Dela Cruz, 18 days ago
Human papillomavirus (HPV) vaccination demonstrates efficacy against oral HPV infections among young adults, although the low uptake limits the population-level effectiveness of the vaccine, according to a cross-sectional study presented at the 2017 ASCO Annual Meeting in Chicago.
Special Reports
01 Mar 2017
At the recent Asia Pacific Alliance for the Control of Influenza (APACI) workshop in Kuala Lumpur, MIMS Doctor had the privilege of having an exclusive interview with eminent paediatric infectious disease specialist, Associate Professor Tawee Chotpitayasunondh. This article captures the highlights from our conversation with him.
Stephen Padilla, 06 Dec 2016
Dengvaxia, a recombinant, live-attenuated dengue vaccine, has the potential to bring down the number of hospitalizations by 13 to 25 percent and be cost-effective in areas of moderate-to-high dengue endemicity, according to a model comparison study.
02 Dec 2016
The Asia Pacific Alliance for the Control of Influenza (APACI) recently organized an influenza workshop in Kuala Lumpur. The workshop saw eminent speakers from seven countries presenting on topics concerning the impact of influenza, vaccination of various populations, current and upcoming treatments for influenza, policy considerations and approaches for pandemic preparedness. Read about highlights from the workshop in this newsletter. 
23 Nov 2016
At the recent Infectious Disease Symposium held on the 5th of August 2016, at Le Meridien Kuala Lumpur, two speakers spoke on the role of macrolides in the management of respiratory tract infections, as well as the importance of antibiotic stewardship in combating microbial resistance.
Dr. Joslyn Ngu, 19 Aug 2016

The rise of anti-malarial resistant Plasmodium falciparum in areas where malaria is endemic, such as Southeast Asia, calls for the safe and right use of current antimalarials.

30 Jul 2016
Antimicrobial resistance is an increasingly serious threat to global public health. To address this, Associate Professor de Castro recently sat down with MIMS Doctor to give her views on the judicious use of antimicrobial agents.
Roshini Claire Anthony, 05 Jul 2016

Renal transplant recipients have a high incidence of hospitalization due to pyelonephritis, according to a Danish population-based cohort study.

Conference Reports
Pearl Toh, 09 Mar 2017
Pearl Toh finds out from Professor Anna Lok, director of clinical hepatology at the University of Michigan in Ann Arbor, Michigan, US, on integrating guidelines, research data, and clinical setting in decision making for management of hepatitis B during the recent Asian Pacific Association for the Study of the Liver Annual Meeting held in Shanghai, China.

Pearl Toh, 08 Mar 2017
Add-on of pegylated interferon (pegIFN) to nucleos(t)ide analogues (NA) therapy may be a better strategy than a switch from NA to pegIFN in patients with chronic hepatitis B (CHB) who are on long-term NA therapy, according to data from an interim analysis of the SWAP* study presented at the recent Asian Pacific Association for the Study of the Liver Annual Meeting (APASL 2017) held in Shanghai, China.
Pearl Toh, 24 Feb 2017
The goal of treatment for portal hypertension varies depending on the different stages and substages of cirrhosis, and hence, pharmacological therapies for managing portal hypertension should be considered in the context of other complications of cirrhosis, according to a presentation at the recent APASL 2017 held in Shanghai, China recently.
24 Feb 2017
Slideshow: Highlights from the 26th Conference of the Asian Pacific Association for the Study of the Liver (APASL), Shanghai, China, February 15 - 19.
Roshini Claire Anthony, 23 Feb 2017

The use of statins is associated with a lower risk of pyogenic liver abscess, according to a Taiwan population-based case-control study. 

Roshini Claire Anthony, 22 Feb 2017

Individuals with hepatitis C virus (HCV) infection who achieve a sustained virological response (SVR) have improved liver stiffness and a lower risk of hepatocellular carcinoma (HCC), according to a presentation at the Asian Pacific Association for the Study of the Liver annual meeting (APASL 2017) in Shanghai, China.

Jairia Dela Cruz, 22 Feb 2017
An 8- to 16-week treatment regimen of elbasvir/grazoprevir plus sofosbuvir with or without ribavirin appears to be highly effective and well tolerated in both treatment-naïve and treatment-experienced cirrhotic patients with hepatitis C virus (HCV) genotype 3 (GT3) infection, according to the results of the C-ISLE study presented at the 26th Conference of the Asian Pacific Association for the Study of the Liver (APASL) held in Shanghai, China.