Cholestatic jaundice is a potentially serious condition that may be associated with significant pathology involving the hepato-pancreatico-biliary system that merits early recognition, evaluation and management. Awareness and early detection of cholestatic jaundice at primary care level, followed by appropriate referral to a paediatric gastroenterology centre is crucial in avoiding delay and achieving optimal patient outcomes.
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Adjunct boceprevir is effective for patients with human immunodeficiency virus (HIV) and hepatitis C virus (HCV)-genotype-1 coinfection unresponsive to pegylated interferon/ribavarin (PEGIFN/RBV) therapy, as shown in a retrospective study.