New drug applications approved by US FDA as of 1 - 15 August 2017 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.
A high burden of metabolic risk factors may increase the risk of hepatocellular carcinoma (HCC) in men with chronic hepatitis B virus (HBV) infection, a study has shown. Importantly, smoking exerts a significant effect on the said association.
Multiple consecutive endoscopies with persistent non-neoplastic Barrett’s oesophagus do not appear to be a protective factor against the risk of oesophageal adenocarcinoma (EAC), according to a team of US-based investigators.
Faecal microbiota transplant (FMT) is more effective than placebo for induction of remission in patients with ulcerative colitis (UC), while having no major short-term safety signals, according to a meta-analysis.
Corticosteroids combined with the antibiotic moxifloxacin may be effective for the management of acute acalculous cholecystitis (AAC) with systemic lupus erythematosus (SLE), suggests a new observational study.
Strenuous exercise appears to exert a negative, albeit reversible, impact on gastrointestinal integrity and function, according to a team of Australia-based researchers. The extent of the said gastrointestinal changes may increase further depending on the intensity and duration of exercise.
In patients with ulcerative colitis (UC), induction treatment with 3.2 mg mesalazine using two 1,600 mg tablets once-daily is as good as using four 400 mg tablets twice-daily, according to the results of a noninferority trial.
New drug applications approved by US FDA as of 16 - 30 June 2017 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.
Both video capsule endoscopy (VCE) and computed tomography enterography (CTE) complement each other in the diagnosis of potential small bowel (SB) bleeding, suggests a recent study. Clinicians should consider CTE when VCE is negative.
One in 7 patients diagnosed with colorectal cancer (CRC) are below the recommended average-risk screening age of 50, according to a population-based cohort study, which suggests the need for CRC screening policy changes.
A once-daily oral dose of the direct-acting antiviral agents (DAAs) ledipasvir/sofosbuvir (LDV/SOF) is safe and effective in treating adolescent genotype 1 (GT1) hepatitis C (HCV) patients, according to results of astudy presented at the annual meeting of the European Association for the Study of the Liver (EASL) International Liver Congress™ (ILC) 2016 in Barcelona, Spain.