Intravenous terlipressin infusion appears to be the most effective medical therapy for reversing hepatorenal syndrome, while intravenous noradrenaline infusion is an acceptable alternative, according to a study.
Fructans exacerbate several symptoms of irritable bowel syndrome (IBS) in children, a study has shown. However, those with fructan sensitivity cannot be identified based on baseline gastrointestinal symptoms, dietary intake, psychosocial factors or gas production.
A study recently conducted by the Chinese University of Hong Kong (CUHK) in collaboration with the University of Calgary, Alberta, Canada, revealed a trend of increasing incidence of inflammatory bowel disease (IBD) including ulcerative colitis (UC) and Crohn’s disease (CD) in regions other that the West, with the incidence in Hong Kong increasing more than 30 times over the past 30 years.
Having both type 1 diabetes and coeliac disease (CD) autoimmunity in early childhood appears to be more common than expected, with the development of islet autoantibodies (IAs) conferring a significant risk of subsequent tissue transglutaminase autoantibodies (tTGAs), according to data from the TEDDY* study.
Pancreatoscopy is effective and well tolerated in patients with difficult to manage stone disease, strictures and possible malignant ductal pathology, facilitating both diagnosis and therapy, according to a recent study.
New drug applications approved by US FDA as of 1 - 15 October 2017 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.
In pregnant women, adherence to recommended dietary intake of fat and fibre is associated with a more beneficial and richer gut microbiota which, in turn, decreases levels of the inflammation marker glycoprotein acetylation (GlycA), a study has shown.
Bisphosphonates have proven antifracture efficacy and remain to be the cornerstone of osteoporosis treatment. However, a drug holiday is of particular importance with bisphosphonates due to some signals with long-term use of the drug, including rare incidence of atypical femoral fracture (AFF) and osteonecrosis of the jaw (ONJ), says a leading endocrinologist at AFOS 2017.
Breast cancer patients have notably different microbiomes in the local breast tissue and urinary tract, a recent study reveals. Particularly, species in the Methylobacterium genus are reduced in the local breast tissue while the urinary tract is enriched in gram-positive bacteria.
Statin use, particularly in smokers, obese patients and nondiabetics, has a strong and dose-dependent association with decreasing risk of pancreatic ductal adenocarcinoma (PDAC), according to a new study.