Top Medical News
11 hours ago
A low rate of metabolic clearance of insulin (MCRI) in nonobese, healthy Japanese males is correlated with increased adiposity, reduced fitness and defective insulin sensitivity of the muscles, a new study shows.
Pearl Toh, Yesterday
Achieving a stringent glycated haemoglobin (HbA1c) goal of <6.5 percent within 6 months of metformin initiation was associated with a decreased risk of cardiovascular (CV) events and mortality in real-world patients with type 2 diabetes, with a greater magnitude of HbA1c reduction being predictive of a lower outcome risk, according to a large Danish registry-based study.
Tristan Manalac, Yesterday
The plasma-free amino acid (PFAA) profile predicts dyslipidaemia, hyperinsulinaemia and hyperglycaemia in healthy Singaporean adults, a new cross-sectional study reveals. Moreover, changes in this profile are correlated with central adiposity.
Yesterday
Early detection of diabetic foot ulcer and early screening to assess grade and stage severity are important predictors of healing time, a new retrospective cohort study shows.
Jairia Dela Cruz, 2 days ago
Pioglitazone may effectively reduce the risk of acute coronary syndrome (ACS) following a cerebrovascular event among patients with insulin resistance (IR) but without diabetes mellitus, with the most prominent effect observed on spontaneous type 1 myocardial infarctions, according to a secondary analysis of the IRIS* trial.
2 days ago
Maternal familial history (FH) of diabetes is independently correlated with poor glycaemic control in patients with type 2 diabetes (T2D), a new study reveals.
Stephen Padilla, 2 days ago
Muslim patients with diabetes mellitus (DM) who fast during Ramadan apply unsafe self-management practices, according to a Singapore study.
Special Reports
05 Apr 2017
At a recent lunch symposium held in conjunction with the 1st Malaysian Advances in Women’s Health Congress 2016, Professor Dr Jamiyah Hassan imparted clinical updates and strategies for the optimization of hormone replacement therapy in menopausal women. Highlights from her presentation are summarized below.
16 Mar 2017
Recently, Dr Peter Lin of the Canadian Heart Research Centre spoke on treatment strategies in the management of dyslipidaemia and T2DM at an AstraZeneca-sponsored continuing medical education event. Highlights of his presentations are summarized below.
20 Jan 2017
At the recent Malaysian Osteoporosis Society 2016 Clinical Practice Guideline (CPG) Meeting held on the 8th of October 2016 at Ibis Styles Ipoh, Dr Hew Fen Lee and Professor Dr Chan Siew Pheng presented clinical guidance on the management of osteoporosis, and discussed whether the benefits of treatment outweigh the risks.
04 Jan 2017
At the Diabetes Asia 2016 Conference organized by the National Diabetes Institute, Professor Jean Claude Mbanya presented the case for why gliclazide modified release (MR; Diamicron® MR, Servier) should be the treatment of choice for early and aggressive control of type 2 diabetes (T2D).
16 Dec 2016
BASALOG – Insulin glargine (rDNA) 100 IU/mL soln for inj (cartridge) – CCM Pharmaceuticals
16 Dec 2016
INVOKANA – Canagliflozin hemihydrate 100 mg and 300 mg FC tab – Johnson & Johnson (Janssen)
Pearl Toh, 07 Dec 2016
Preventing hypertension, diabetes, and obesity, which are the major risk factors for heart failure (HF), by ages 45 and 55 years may lower risks of incident HF and prolong HF-free survival, suggests data from the Cardiovascular Disease Lifetime Risk Pooling Project.
Conference Reports
Pearl Toh, 21 Nov 2016
Combining bone cortical porosity and trabecular density in assessment of structural deterioration (known as structural fragility score [SFS]) identifies women with imminent fracture risk better than using the fracture risk-assessment tool (FRAX) or bone mineral density (BMD), according to the OFELY* study presented at the 6th Asia-Pacific Osteoporosis Meeting (IOF Regionals 2016) held in Singapore.
Tristan Manalac, 17 Nov 2016
Diabetes and osteoporosis, particularly bone loss, have very complex pathophysiologies, according to an expert who gave a rundown of the current state of osteoporosis and diabetes at the recently concluded 6th Asia-Pacific Osteoporosis Meeting (IOF Regionals 2016) in Singapore.
Pearl Toh, 16 Nov 2016
Denosumab continuously increases bone mineral density (BMD) at the spine and hip over 10 years, and long-term treatment is associated with reduced incidence of both vertebral and nonvertebral fractures, according to a presentation at the 6th Asia-Pacific Osteoporosis Meeting (IOF Regionals 2016) held in Singapore.
16 Nov 2016
The incidence of denosumab-related hypocalcaemia in postmenopausal women with osteoporosis appears to be higher in real-life clinical settings than what is reported in clinical trials. However, a protocol that requires assessment and replacement of vitamin D, calcium and creatinine levels in all patients prescribed denosumab lowers the incidence, according to a study presented at the 6th Asia-Pacific Osteoporosis Meeting (IOF Regionals 2016) in Singapore.
Roshini Claire Anthony, 15 Nov 2016

Adherence to treatment reduces but does not eliminate the risk of refracture in Asian patients with osteoporosis, according to a presentation at the 6th Asia-Pacific Osteoporosis Meeting (IOF Regionals 2016) held in Singapore.

Roshini Claire Anthony, 09 Nov 2016

The combination of age, weight, menopausal status, chronic joint pain, and right handgrip strength is a good tool to predict spinal osteoporosis in midlife Asian women, and may be an improvement over the Osteoporosis Self-assessment Tool for Asians (OSTA), according to a study presented at the 6th Asia-Pacific Osteoporosis Meeting (IOF Regionals 2016) held recently in Singapore.

Roshini Claire Anthony, 08 Nov 2016

Osteoporosis treatment should not be initiated unless the patient concerned has a sufficiently high risk of fracture, according to a presentation at the 6th Asia-Pacific Osteoporosis Meeting (IOF Regionals 2016) held in Singapore.

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