dyspepsia
DYSPEPSIA

Dyspepsia is having any one of the following: disturbing postprandial fullness, early satiation, epigastric pain and/or burning felt predominantly in the upper abdomen.

It is considered a symptom complex rather than a specific diagnosis.

Acid suppression is the recommended initial therapy.

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  3. Moayyedi P, Soo S, Deeks L, et al. Pharmacological interventions for non-ulcer dyspepsia [abstract]. Cochrane Database Syst Rev. 2003(1):CD001960. PMID: 12535421
  4. Schroeder BM. Evaluation of epigastric discomfort and management of dyspepsia and GERD. Am Fam Physician. 2003 Sep;68(6):1215-1220. PMID: 14524407
  5. Talley NJ. Dyspepsia: management guidelines for the millennium. Gut. 2002 May;50(Suppl 4):iv72-78. PMID: 11953354
  6. Simren M, Tack J. Functional dyspepsia: evaluation and treatment. Gastroenterol Clin North Am. 2003 Jun;32(2):577-599. PMID: 12858607
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  8. Talley NJ. Update on the role of drug therapy in non-ulcer dyspepsia. Rev Gastroenterol Disord. 2003;3(1):25-30. PMID: 12684590
  9. Talley NJ, Silverstein MD, Agréus L, Nyrén O, Sonnenberg A, Holtmann G. AGA technical review: evaluation of dyspepsia. Gastroenterology. 1998 Mar;114(3):582-595. PMID: 9496950
  10. Soll AH, Graham DY. Approach to the patient with dyspepsia and peptic ulcer disease. In: Yamada T, Alpers DH, Kalloo AN, eds. Principles of clinical gastroenterology. 1st ed. West Sussex; 2008
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  12. MedWormhttp://www.medworm.com/rss/index.php/Pediatrics/33/http://www.medworm.com/rss/medicalfeeds/specialities/Pediatrics.xml
  13. Scottish Intercollegiate Guidelines Network. Dyspepsia. A national clinical guideline. SIGN. http://www.guideline.gov/content.aspx?id=3723. Mar 2003
  14. National Institute for Health and Care Excellence. Dyspepsia: Managing dyspepsia in adults in primary care. NICE. http://www.nice.org.uk. Aug 2004
  15. North of England Dyspepsia Guideline Development Group. Dyspepsia: managing dyspepsia in adults in primary care: evidence-based clinical practice guideline. http://www.nice.org.uk/nicemedia/pdf/cg017fullguideline.pdf. Aug 2004
  16. New Zealand Guidelines Group. Management of dyspepsia and heartburn: evidence-based practice guideline. http://www.health.govt.nz/publication/management-dyspepsia-and-heartburn. Jun 2004
  17. Longstreth GF, Lacy BE. Approach to the adult with dyspepsia. UpToDate. http://www.uptodate.com/contents/approach-to-the-adult-with-dyspepsia#H63380126. 28 Aug 2013. Accessed 20 Jan 2014
  18. Loyd RA, McClellan DA. Update on the evaluation and management of functional dyspepsia. Am Fam Physician. 2011;83(5):547-552. http://www.aafp.org/afp/2011/0301/p547.pdf. Accessed 20 Jan 2014. PMID: 21391521
  19. Miwa H, Kusano M, Arisawa T, et al; Japanese Society of Gastroenterology. Evidence-based clinical practice guidelines for functional dyspepsia. J Gastroenterol. 2015 Feb;50(2):125-139. doi: 10.1007/s00535-014-1022-3. PMID: 25586651
  20. Tack J, Camilleri M, Chang L, et al. Systematic review: cardiovascular safety profile of 5-HT(4) agonists developed for gastrointestinal disorders. Aliment Pharmacol Ther. 2012 Apr;35(7):745-767. doi: 10.1111/j.1365-2036.2012.05011.x. PMID: 22356640
  21. Wiśniowska B, Tylutki Z, Wyszogrodzka G, et al. Drug-drug interactions and QT prolongation as a commonly assessed cardiac effect - comprehensive overview of clinical trials. BMC Pharmacol Toxicol. 2016 Mar 10;17:12. doi: 10.1186/s40360-016-0053-1. PMID: 26960809
  22. Stanghellini V, Chan FK, Hasler WL, et al. Gastroduodenal disorders. Gastroenterology. 2016 May;150(6):1380-1392. doi: 10.1053/j.gastro.2016.02.011. PMID: 27147122
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