dyslipidemia
DYSLIPIDEMIA
Dyslipidemia is having an abnormal amount of lipids or fats in the blood.
Lipid profile is obtained from an individual with diabetes mellitus, coronary heart disease, cerebrovascular disease, peripheral arterial disease or other coronary heart disease risk factors or from an individual with family history or clinical evidence of familial hypercholesterolemia.
Plasma lipids are total cholesterol, high-density lipoprotein cholesterol, trigylcerides, and low-density lipoprotein cholesterol.
Evaluation of lipid profile must be performed in parallel with the risk assessment of coronary heart disease.

Definition

  • An abnormality in lipoprotein metabolism that results in elevations of low density lipoprotein-cholesterol(LDL-C), total cholesterol (TC), triglycerides (TG), and/or non-high-density lipoprotein-cholesterol (non-HDL-C) levels, or significantly reduced high-density lipoprotein-cholesterol (HDL-C) levels
  • Increase in serum concentration of TC, LDL, TG or non-HDL-C are equivalent to increased risk for cardiovascular diseases

Etiology

  • Depends on the type of dyslipidemia
  • Hereditary disorders associated with dyslipidemia include familial hypertriglyceridemia, familial combined hyperlipidemia, familial dysbetalipoproteinemia, chylomicronemia
  • Secondary causes include diabetes mellitus, diet, alcohol intake, hypothyroidism, renal failure, medications (glucocorticoids, beta-blockers, thiazides, estrogen therapy)
Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Endocrinology - Malaysia digital copy today!
DOWNLOAD
Editor's Recommendations
Most Read Articles
one year ago
Painful diabetic neuropathy (PDN) is one of the many complications of diabetes. At the Diabetes Asia 2015 Conference, renowned speaker Dr Mary Cardosa gave an overview on PDN and the approaches to managing this condition.
one year ago
Sevelamer increases serum magnesium levels and reduces risk of hypomagnesemia in end-stage renal disease patients requiring haemodialysis, according to a study.
one year ago
Pioglitazone reduces risk for stroke or myocardial infaction (MI) in patients with history of ischaemic stroke or transient ischaemic attack (TIA), based on a multicentre, double-blind trial.
Rachel Soon, one year ago

The inclusion of statins in managing chronic kidney disease (CKD) may help reduce patient mortality from stroke and possibly other cardiovascular events, according to an expert at the 7th Malaysian Endocrine and Metabolic Society (MEMS) Annual Congress.