dyslipidemia
DYSLIPIDEMIA
Dyslipidemia is having an abnormal amount of lipids or fats in the blood.
Lipid profile is obtained from an individual with diabetes mellitus, coronary heart disease, cerebrovascular disease, peripheral arterial disease or other coronary heart disease risk factors or from an individual with family history or clinical evidence of familial hypercholesterolemia.
Plasma lipids are total cholesterol, high-density lipoprotein cholesterol, trigylcerides, and low-density lipoprotein cholesterol.
Evaluation of lipid profile must be performed in parallel with the risk assessment of coronary heart disease.

Definition

  • An abnormality in lipoprotein metabolism that results in elevations of low density lipoprotein-cholesterol(LDL-C), total cholesterol (TC), triglycerides (TG), and/or non-high-density lipoprotein-cholesterol (non-HDL-C) levels, or significantly reduced high-density lipoprotein-cholesterol (HDL-C) levels
  • Increase in serum concentration of TC, LDL, TG or non-HDL-C are equivalent to increased risk for cardiovascular diseases

Etiology

  • Depends on the type of dyslipidemia
  • Hereditary disorders associated with dyslipidemia include familial hypertriglyceridemia, familial combined hyperlipidemia, familial dysbetalipoproteinemia, chylomicronemia
  • Secondary causes include diabetes mellitus, diet, alcohol intake, hypothyroidism, renal failure, medications (glucocorticoids, beta-blockers, thiazides, estrogen therapy)
Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Cardiology - Malaysia digital copy today!
DOWNLOAD
Editor's Recommendations
Most Read Articles
one year ago
Long-term pegvisomant treatment enhances cardiac and respiratory comorbidities in acromegalic patients based on a retrospective single-centre study.
one year ago
New drug applications approved by US FDA as of 16 - 31 Dec 2015 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.
Roshini Claire Anthony, 4 months ago

Individuals with a history of migraine may be at a higher risk for ischaemic stroke within 1 month postsurgery, a recent study found.

Kathlin Ambrose, one year ago

Doctors uncertain on which cardiovascular (CV) risk calculator to use may consider opting for the Framingham General CV Disease risk score as studies have been performed in the country to validate it, says an expert.