Immune-mediated antitumour responses may aid tumour control following conventional chemotherapy and natural killer (NK) cells have been shown to be particularly important in this respect in multiple myeloma (MM). Now, a recent study has shown that inhibition of BET proteins or CBP/EP300 can increase the expression of MICA, a NK cell-activating ligand, in MM cells, and could, therefore, improve both direct and immune-mediated antitumour activity in MM.
EGFR-ASAP1 signalling may contribute to hepatoblastoma (HBL) tumorigenesis and invasiveness, say US-based researchers.
Laparoscopic liver resection (LLR) is safe and effective when performed by expert laparoscopic surgeons, a recent study found.
Chemotherapy is associated with better overall survival (OS) in patients with advanced angiosarcoma, though only a select number receive this treatment, according to findings from the first collaborative study by the Asian Sarcoma Consortium (ASC).