Top Medical News
Pearl Toh, Yesterday
Transcatheter aortic valve replacement (TAVR) with a self-expanding prosthesis is noninferior to surgical aortic valve replacement (SAVR) in terms of death from any cause or disabling stroke at 2 years in intermediate-risk patients with severe aortic stenosis (AS), according to data from the SURTAVI* trial presented at the ACC.17 held in Washington, DC, US.
Yesterday
Hypertrophic cardiomyopathy (HCM) patients with severe right ventricular hypertrophy (SRVH) are characterized by mutations in sarcomere- and ion-channel disease-related genesand poor clinical outcomes, a new study details.
Stephen Padilla, Yesterday
A Mendelian randomization approach has disproved observational studies showing that dairy intake is associated with lower systolic blood pressure (SBP) and lower risk of hypertension.
Yesterday
Shorter sleep duration appears to elevate the risk of mortality associated with hypertension, suggests a new study. Moreover, short sleep in hypertensive individuals may indicate the degree of central autonomic dysfunction.
Yesterday
Angiotensin receptor blockers (ARBs) appear to provide better protection against cardiovascular (CV) events compared with ACE inhibitors (ACEIs) in patients with established CV disease, according to a study.
Jairia Dela Cruz, 2 days ago
Use of phosphodiesterase-5 (PDE5) inhibitors following a first myocardial infarction (MI) may reduce the risk of long-term adverse outcomes, including mortality and heart failure hospitalization, in a dose-dependent fashion, according to a Swedish study.
2 days ago
Exosomal microRNAs (miRNAs) in the serum are potential diagnostic biomarkers for Kawasaki disease (KD), a new study shows.
Special Reports
16 Mar 2017
Recently, Dr Peter Lin of the Canadian Heart Research Centre spoke on treatment strategies in the management of dyslipidaemia and T2DM at an AstraZeneca-sponsored continuing medical education event. Highlights of his presentations are summarized below.
07 Mar 2017
At the 17th Malaysian Society of Rheumatology/Singapore Society of Rheumatology Workshop, Associate Professor Susanna Proudman, a senior consultant in rheumatology from Australia, shared with the audience on the diagnosis and management of pulmonary arterial hypertension (PAH), with a focus on systemic sclerosis (SSc)-related PAH.
16 Feb 2017
At the recent launch of an exclusive guidebook on vasodilating β-blockers for the treatment of hypertension and chronic heart failure (HF), Professor Athanasios J. Manolis delivered a lecture on why nebivolol is different from the other agents in its class.
16 Dec 2016
During the 8th Diabetes Complications Conference & Grand Rounds 2016, Dr Azani Mohamed Daud talked about the guidelines on the use of ACEIs and ARBs in hypertension, and highlighted their clinical efficacies for hypertension treatment.
Prof. Abdul Rashid, Prof. Martin Strauss, Prof. Alistair Hall, 12 Dec 2016
Hypertension is a leading cause of mortality globally and is of particular concern in the Asia Pacific region where there are more deaths due to poor blood pressure (BP) control than in any other region in the world. At a recent Servier-sponsored satellite symposium held during the ASEAN Federation of Cardiology Congress in Yangon, Myanmar, Professor Abdul Rashid, An Nur Specialist Hospital, Selangor, Malaysia, discussed the challenges associated with managing hypertension in the region. In addition, Professor Martin Strauss, North York General Hospital, Toronto, Canada and Professor Alistair Hall, Leeds General Infirmary, UK, discussed the different effects of angiotensin converting enzyme (ACE) inhibitors and angiotensin II receptor blockers (ARBs) on cardiovascular (CV) outcomes, highlighting the additional protection against myocardial infarction (MI) offered by ACE inhibitors such as perindopril.
Pearl Toh, 07 Dec 2016
Preventing hypertension, diabetes, and obesity, which are the major risk factors for heart failure (HF), by ages 45 and 55 years may lower risks of incident HF and prolong HF-free survival, suggests data from the Cardiovascular Disease Lifetime Risk Pooling Project.
Roshini Claire Anthony, 25 Nov 2016

The addition of evolocumab to statin therapy in individuals with angiographic coronary disease appeared to encourage coronary atherosclerosis regression, as demonstrated in the GLAGOV* trial presented at the Scientific Sessions of the American Heart Association (AHA 2016) held in New Orleans, Louisiana, US.

Conference Reports
Pearl Toh, 23 Mar 2017
Transcatheter aortic valve replacement (TAVR) with a self-expanding prosthesis is noninferior to surgical aortic valve replacement (SAVR) in terms of death from any cause or disabling stroke at 2 years in intermediate-risk patients with severe aortic stenosis (AS), according to data from the SURTAVI* trial presented at the ACC.17 held in Washington, DC, US.
Audrey Abella, 22 Mar 2017
Fractional flow reserve (FFR)-guided complete revascularization of non-infarct-related arteries in acute primary percutaneous coronary intervention (PCI) reduced the risk of cardiovascular outcomes compared with treating infarct-related arteries (IRA) only, according to the Compare-Acute* trial presented at the American College of Cardiology’s (ACC) 66th Annual Scientific Session held in Washington, DC, US.
Roshini Claire Anthony, 21 Mar 2017

Prophylactic infusion of levosimendan did not reduce death or perioperative myocardial infarction or the need for dialysis or mechanical cardiac assist device more than placebo in patients at risk for low cardiac output syndrome undergoing cardiac bypass. However, it increased cardiac output and reduced low cardiac output syndrome, according to primary findings of the LEVO-CTS* trial. 

Pearl Toh, 21 Mar 2017
Intensive LDL lowering through the addition of the PCSK9* inhibitor evolocumab to statin therapy significantly reduced the risk of cardiovascular (CV) events in patients with existing atherosclerotic CV disease, according to data from the FOURIER** trial presented at the American College of Cardiology’s 66th Annual Scientific Session (ACC.17) held in Washington, DC, US.
Dr. Angela V. Ignacio, 20 Mar 2017
Obstructive sleep apnoea (OSA) and central sleep apnoea (CSA) appear to occur in nearly half and one-tenth of patients with acute myocardial infarction (AMI), respectively, and may resolve or change from one type to another in the 6 months following AMI, according to results of a Singaporean study presented at the American College of Cardiology’s 66th Annual Scientific Session in Washington, D.C.
Dr. Angela V. Ignacio, 20 Mar 2017
Among breast cancer survivors, engaging in high levels of physical activity before or around the time of diagnosis may decrease the risk of developing cardiovascular events (CVE) and dying from coronary heart disease (CHD) after receiving cancer therapy, according to a study presented at the American College of Cardiology’s 66th Annual Scientific Session in Washington, DC.
Pearl Toh, 10 Mar 2017
Contact aspiration is comparable to stent retriever (SR) as frontline thrombectomy for patients with acute ischaemic stroke resulting from large vessel occlusion (LVO), according to the ASTER* trial presented at the recent International Stroke Conference (ISC 2017) held in Texas, Houston, US.
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